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Test-Based Nutrition, Chronic Inflammation and Gut Health

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With Dr Paul Clayton

Clinical pharmacologist and pharmaco-nutritionist

His pharmacological background brings questions of mechanism, dose, interaction, timing, evidence and measurable response into nutrition.

  • Understand how inflammation, gut biology and nutrition connect across the body.
  • Put test results inside a wider health and professional context.
  • Hear Dr Clayton’s answers to questions from the professional community.

The recording is now available. Leave your details below to receive the link by email and watch whenever it suits you. You are welcome to share this registration page with colleagues who would value the conversation.

RECORDING AVAILABLE

Watch in your own time.

Our conversation with Dr Paul Clayton took place on 18 October 2026. The recording includes the presentation and questions from participants.

This is a free educational recording. Request it below and I’ll send you the link by email.

THE QUESTION BEHIND THE SESSION

We have more medicine, more testing and more health information than ever. Why are chronic conditions still increasing, and appearing earlier?

Dr Clayton’s work directs attention to the years before a diagnosis, when low-grade inflammation, altered immune regulation, microbial changes, nutritional insufficiencies and metabolic dysfunction may already be changing the body.

01

WHY DR PAUL CLAYTON

Nutrition examined through the discipline of pharmacology.

Dr Paul Clayton

Dr Paul Clayton is a clinical pharmacologist and pharmaco-nutritionist. He graduated summa cum laude in Medical Pharmacology from the University of Edinburgh before completing his PhD.

He is a former Chair of the Forum on Food & Health and a former Senior Scientific Advisor to the UK government’s Committee on the Safety of Medicines. He has worked internationally with doctors and clinical scientists, helping to design and supervise pre-clinical and clinical studies of pharmaco-nutritional interventions.

In 2022, he was recognised in the Doctor-to-Doctor World’s Top 100, a peer-nominated international recognition for contribution to healthcare, science, innovation and professional leadership.

His value is not simply that he speaks about nutrition. His pharmacological background brings questions of mechanism, dose, interaction, timing, evidence and measurable response into a field too often reduced to generic advice.

A DIFFERENT STARTING POINT

The stronger question is not simply “What should I eat?” It is: what is already changing in the body, how can we recognise it earlier, and what can still be influenced?

02

THE SCIENCE BEHIND THE CONVERSATION

Not isolated symptoms. Connected biological processes.

These questions reflect the central areas of Dr Clayton’s research, writing and teaching.

01

What happens before disease becomes visible?

Chronic conditions rarely begin when symptoms first appear. Silent biological changes may develop for years before a diagnosis, which is why prevention must begin earlier than most people realise.

02

When does protective inflammation become damaging?

Acute inflammation is essential. Persistent low-grade inflammation is different. Understanding what may prevent inflammatory processes from resolving helps explain why their effects can appear across seemingly unrelated body systems.

03

Why is the microbiome relevant far beyond digestion?

The gut microbiome interacts with the intestinal barrier, immune system, metabolism, inflammatory signalling and compounds involved in communication with the brain. Gut health therefore cannot be understood as an isolated digestive issue.

04

Why can the same advice produce different results?

Food intake is only one part of nutrition. Digestion, absorption, age, medication, stress, microbial activity, nutrient reserves and existing health conditions all influence the result. Personalisation begins by recognising those differences.

05

What can testing add, and what can it not tell us?

Testing does not explain every symptom and does not replace medical care. Used responsibly, it can reduce guesswork, identify measurable patterns, guide more precise decisions and show whether an intervention is creating the intended change.

06

Can we protect healthspan, not simply extend lifespan?

The deeper goal of prevention is to preserve function, resilience, cognition, mobility and independence. That requires attention to the biological foundations of later health long before decline is considered inevitable.

03

PHARMACO-NUTRITION

More precise than calling a nutrient “healthy”.

Pharmaco-nutrition considers how nutrients and bioactive compounds may influence biological pathways in specific and clinically meaningful ways.

It asks more demanding questions: Which mechanism is being targeted? Is the amount biologically relevant? How do nutrients interact? How can the response be assessed? When is nutritional support appropriate, and when is medical evaluation needed?

This is what makes Dr Clayton’s work valuable to professionals and health-conscious individuals alike. It replaces simplistic promises with a stronger framework for thinking, measuring and deciding.

FOR PROFESSIONALS

A framework for complex cases.

For health and wellness professionals, the recording offers a way to explore how apparently separate concerns may share biological mechanisms, where testing may add meaningful information, and how to distinguish responsible personalisation from unsupported assumptions.

  • Connect symptoms without reducing everything to one cause.
  • Think more precisely about inflammation, microbial activity and nutrient status.
  • Place measurements inside a wider clinical and human context.
  • Communicate complex science without overpromising.

FOR HEALTH ENTHUSIASTS

A clearer map of your own health.

For people interested in their own health, this is an opportunity to understand why persistent concerns are not always solved by another generic diet, supplement list or wellness trend.

  • Understand why one symptom may have several contributing factors.
  • See how the gut, immunity, metabolism and brain communicate.
  • Learn where personal data may be more useful than assumptions.
  • Ask better questions without fear or unrealistic promises.

04

QUESTIONS & DISCUSSION

Hear the questions from our conversation.

The recording includes Dr Clayton’s discussion with participants about nutrition, chronic inflammation, gut health and questions from their own health and professional work.

If something comes to mind while watching, you are welcome to email me. You can also leave a message or question when requesting the recording.

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